The active ingredient in Esomeprazole Magnesium Delayed Release Capsules 20 mg is esomeprazole magnesium, 20 mg, acid reducer. Each delayed-release capsule corresponds to 22 mg esomeprazole magnesium dihydrate. Taken once every 24 hours for 14 days, this capsule is clinically proven to treat frequent heartburn occurring 2 or more days per week. Esomeprazole Magnesium Delayed Release Capsules 20 mg is not intended for immediate relief of heartburn; this drug may take 1 to 4 days for full effect.Safety Warning:-Had heartburn over 3 months. This may be a sign of a more serious condition-Frequent wheezing, particularly with heartbur-Unexplained weight loss-Nausea or vomiting-Stomach painAsk a doctor or pharmacist before use if you are taking warfarin, clopidogrel or cilostazol (blood-thinning medicines); prescription antifungal or anti-yeast medicines; digoxin (heart medicine); diazepam (anxiety medicine); tacrolimus or mycophenolate mofetil (immune system medicines); prescription antiretrovirals (medicines for HIV infection); methotrexate (arthritis medicine). Stop use and ask a doctor if your heartburn continues or worsens; you need to take this product for more than 14 days; you need to take more than 1 course of treatment every 4 months; you get diarrhea. If pregnant or breast-feeding, ask a health professional before use. Keep out of reach of children.